Cities to visit near Louisville?

I am looking for ideas for a weekend getaway - places near Louisville, KY - four to seven hours drive away. We've already been to Lexington, Frankfort, Corbin, Mammoth Caves, Gatlinburg (TN), Cape Lookout (NC), Atlanta (GA) and Nashville (TN) so these places are ruled out. Could someone please suggest any cities in KY or neighbouring states?